Background: Regenerative procedures offer a limited potential toward achieving a complete periodontal regeneration and today, there is not any single material that can be considered as ‘gold standard’ in infra bony defect treatment. Platelet-rich fibrin (PRF) is the second-generation platelet concentrate and represents a slow release system for growth factors. Use of PRF showed promising results in various periodontal surgical procedures. The aim of this report is to describe two-stage treatment of a canine tooth having an infrabony defect accompanied with a deep dehiscence by using PRF-connective tissue graft (CTG) combination. Case Report: A 28-year old man was referred to the Department of Periodontology with chief complaints of purulent exudate formation, tooth mobility in tooth #23 (FDA classification). Deep periodontal pockets in combination with 4 mm buccal recession were detected. Radiographically, a significant radiolucency was also present. CTG graft combined with coronally advanced flap by adding a PRF gel was utilized for the treatment of defect and accompanying gingival recession. Conclusion: Significant improvements were detected at all periodontal clinical and radiographic measurements.

Primary oral mucosa malignant melanoma is a rare and biologically aggressive neoplasm. It is estimated about 1~2% of all oral malignancies with the incidence increasing with age. The prognosis of oral mucosa malignant melanoma is poor with the five-year survival rate is approximately 15%. The diagnosis of oral melanoma is usually delayed because it is always asymptomatic at the beginning and it resembles the epulis, amalgam tattoo or other oral lesions. In addition, nearly a third of all oral melanoma are amelanotic and may lack a radial growth phase, which makes early and accurate diagnosis even difficult. Thus, regional and distant metastases happen more frequently. Surgery is the first choice of treatment, and clinically negative necklymph nodes with neck dissection or radiotherapy are also recommended because of the high risk of subclinical regional metastasis. In this article, we reviewed the clinical features, diagnosis, treatment, and presented a 70 y/o male who suffered from an easily bleeding lesion over right posterior palatal mucosa and gingiva who presented at hospital for help. We performed biopsy which revealed a malignant melanoma. He received supraomohyoid neck lymph node dissection, partial maxillectomy, and was reconstructed with anterior lateral thigh free fascia cutaneous flap. After surgical treatment, the patient kept regular follow-ups. The treatment outcome was good and the patient recovered with full swallowing and phonation function.

Oral health has become a major topic of discussion in the State of Hawaii based on the unreasonably high rates of dental caries in children, which are almost twice the average rates for children living in the mainland. Lack of water fluoridation, absence of a state dental school and recent efforts to start rebuild the previously dismantled oral health branch at the Department of Health may be contributing to these poor oral health outcomes. However, there are many more known caries risk factors which may be socially, physiologically, culturally and economically driven that have yet to be documented within the State of Hawaii. While community assessments may evaluate oral health needs of the overall community, low income and vulnerable populations such as pregnant women and children deserve special attention and priority. Identification of risk factors amenable to change, such as families’ oral health beliefs and behaviors should be clearly documented and considered in the process of developing future oral health initiatives as a means to improve oral health outcomes for children and families in Hawaii.

The purpose of this case report is to compare the clinical and histopathologic features of granular cell ameloblastoma with critical review on literature. Data with respect to the histologic types regarding tumor with higher recurrence rates are also investigated. Numerous cases of ameloblastoma have been reported in the literature. However, only a few articles discuss granular cell ameloblastoma and few closely examine their nature and pathogenesis. In this case report, we analyzed the clinical and histopathologic features of granular cell ameloblastoma.

Peripheral ossifying fibroma is a relatively common gingival growth of reactive rather than neoplastic in nature. Clinically differentiating one from the other as a specific lesion is often difficult and requires histopathology examination. It predominantly affects adolescents and young adults, but rarely seen in infants. We report here a clinical case of peripheral ossifying fibroma in a 3 month old infant .clinical and histopathological features along with etiopathogenesis and differential diagnosis are also discussed.